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RALA-mediated delivery of FKBPL nucleic acid therapeutics

AIMS: RALA is a novel 30 mer bioinspired amphipathic peptide that is showing promise for gene delivery. Here, we used RALA to deliver the FK506-binding protein like – FKBPL gene (pFKBPL) – a novel member of the immunophilin protein family. FKBPL is a secreted protein, with overexpression shown to in...

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Bibliographic Details
Published in:Nanomedicine (Lond)
Main Authors: Bennett, Rachel, Yakkundi, Anita, McKeen, Hayley D, McClements, Lana, McKeogh, Thomas J, McCrudden, Cian M, Arthur, Kenneth, Robson, Tracy, McCarthy, Helen O
Format: Artigo
Language:Inglês
Published: Future Medicine Ltd 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4910961/
https://ncbi.nlm.nih.gov/pubmed/26419658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.15.115
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