The Anti-Migratory Effects of FKBPL and Its Peptide Derivative, AD-01: Regulation of CD44 and the Cytoskeletal Pathway

FK506 binding protein-like (FKBPL) and its peptide derivatives exert potent anti-angiogenic activity in vitro and in vivo and control tumour growth in xenograft models, when administered exogenously. However, the role of endogenous FKBPL in angiogenesis is not well characterised. Here we investigate...

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Main Authors: Yakkundi, Anita, McCallum, Lynn, O’Kane, Anthony, Dyer, Hayder, Worthington, Jenny, McKeen, Hayley D., McClements, Lana, Elliott, Christopher, McCarthy, Helen O., Hirst, David G., Robson, Tracy
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574160/
https://ncbi.nlm.nih.gov/pubmed/23457460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055075
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