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Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study

BACKGROUND: Taxane is one of the first line treatments of lung cancer. In order to identify novel single nucleotide polymorphisms (SNPs) that might contribute to taxane response, we performed a genome-wide association study (GWAS) for two taxanes, paclitaxel and docetaxel, using 276 lymphoblastoid c...

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Autori principali: Niu, Nifang, Schaid, Daniel J, Abo, Ryan P, Kalari, Krishna, Fridley, Brooke L, Feng, Qiping, Jenkins, Gregory, Batzler, Anthony, Brisbin, Abra G, Cunningham, Julie M, Li, Liang, Sun, Zhifu, Yang, Ping, Wang, Liewei
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573965/
https://ncbi.nlm.nih.gov/pubmed/23006423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-422
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