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Molecular Characterization and Functional Activity of an IL-15 Antagonist MutIL-15/Fc Human Fusion Protein

Fc fusion proteins are a new emerging class of molecules for immune-targeted delivery of therapeutic proteins. Biophysical and bioanalytical characterization is critical for clinical development and delivery of therapeutic proteins. Here we report molecular and functional characterization of a recom...

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Detalhes bibliográficos
Main Authors: Yang, Xiaoyi, Kallarakal, Abraham, Saptharishi, Nirmala, Jiang, Hengguang, Yang, Zhiwen, Xie, Yueqing, Mitra, George, Zheng, Xin Xiao, Strom, Terry B., Soman, Gopalan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573692/
https://ncbi.nlm.nih.gov/pubmed/23311475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300513j
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