Therapeutic Efficacy of Antibodies Lacking FcγR against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies

Dengue hemorrhagic fever and dengue shock syndrome (DHF/DSS) are life-threatening complications following infection with one of the four serotypes of dengue virus (DENV). At present, no vaccine or antiviral therapies are available against dengue. Here, we characterized a panel of eight human or mous...

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Autors principals: Williams, Katherine L., Sukupolvi-Petty, Soila, Beltramello, Martina, Johnson, Syd, Sallusto, Federica, Lanzavecchia, Antonio, Diamond, Michael S., Harris, Eva
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573116/
https://ncbi.nlm.nih.gov/pubmed/23459315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003157
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