Dengue virus neutralization is modulated by IgG antibody subclass and Fcγ receptor subtype

Severe dengue virus (DENV) infection is epidemiologically linked to pre-existing anti-DENV antibodies acquired by maternal transfer or primary infection. A possible explanation is that DENV immune complexes evade neutralization by engaging Fcγ receptors (FcγR) on monocytes, natural targets for DENV...

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Main Authors: Rodrigo, W. W. Shanaka I., Block, Olivia KT, Lane, Christopher, Sukupolvi-Petty, Soila, Goncalvez, Ana P., Johnson, Syd, Diamond, Michael S., Lai, Ching-Juh, Rose, Robert C., Jin, Xia, Schlesinger, Jacob J.
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783259/
https://ncbi.nlm.nih.gov/pubmed/19833371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.09.024
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