Berberine Inhibits Proliferation and Down-Regulates Epidermal Growth Factor Receptor through Activation of Cbl in Colon Tumor Cells

Berberine, an isoquinoline alkaloid, is an active component of Ranunculaceae and Papaveraceae plant families. Berberine has been found to suppress growth of several tumor cell lines in vitro through the cell-type-dependent mechanism. Expression and activation of epidermal growth factor receptor (EGF...

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Main Authors: Wang, Lihong, Cao, Hailong, Lu, Ning, Liu, Liping, Wang, Bangmao, Hu, Tianhui, Israel, Dawn A., Peek, Richard M., Polk, D. Brent, Yan, Fang
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573001/
https://ncbi.nlm.nih.gov/pubmed/23457600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056666
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