Berberine Inhibits Proliferation and Down-Regulates Epidermal Growth Factor Receptor through Activation of Cbl in Colon Tumor Cells

Berberine, an isoquinoline alkaloid, is an active component of Ranunculaceae and Papaveraceae plant families. Berberine has been found to suppress growth of several tumor cell lines in vitro through the cell-type-dependent mechanism. Expression and activation of epidermal growth factor receptor (EGF...

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Autores principales: Wang, Lihong, Cao, Hailong, Lu, Ning, Liu, Liping, Wang, Bangmao, Hu, Tianhui, Israel, Dawn A., Peek, Richard M., Polk, D. Brent, Yan, Fang
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573001/
https://ncbi.nlm.nih.gov/pubmed/23457600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056666
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