Activation of Epidermal Growth Factor Receptor Mediates Mucin Production Stimulated by p40, a Lactobacillus rhamnosus GG-derived Protein

The mucus layer coating the gastrointestinal tract serves as the first line of intestinal defense against infection and injury. Probiotics promote mucin production by goblet cells in the intestine. p40, a Lactobacillus rhamnosus GG-derived soluble protein, has been shown to transactivate the EGF rec...

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Bibliografiske detaljer
Main Authors: Wang, Lihong, Cao, Hailong, Liu, Liping, Wang, Bangmao, Walker, W. Allan, Acra, Sari A., Yan, Fang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4106339/
https://ncbi.nlm.nih.gov/pubmed/24895124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.553800
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