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Interplay of Protein and DNA Structure Revealed in Simulations of the lac Operon

The E. coli Lac repressor is the classic textbook example of a protein that attaches to widely spaced sites along a genome and forces the intervening DNA into a loop. The short loops implicated in the regulation of the lac operon suggest the involvement of factors other than DNA and repressor in gen...

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Detalhes bibliográficos
Main Authors: Czapla, Luke, Grosner, Michael A., Swigon, David, Olson, Wilma K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572996/
https://ncbi.nlm.nih.gov/pubmed/23457581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056548
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