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Effects of the nucleoid protein HU on the structure, flexibility, and ring-closure properties of DNA deduced from Monte-Carlo simulations

The histone-like heat unstable HU protein plays a key role in the organization and regulation of the Escherichia coli genome. The non-specific nature of HU binding to DNA complicates analysis of the mechanism by which the protein contributes to the looping of DNA. Conventional models of the looping...

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Detalhes bibliográficos
Main Authors: Czapla, Luke, Swigon, David, Olson, Wilma K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679585/
https://ncbi.nlm.nih.gov/pubmed/18586040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.088
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