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Effects of the nucleoid protein HU on the structure, flexibility, and ring-closure properties of DNA deduced from Monte-Carlo simulations
The histone-like heat unstable HU protein plays a key role in the organization and regulation of the Escherichia coli genome. The non-specific nature of HU binding to DNA complicates analysis of the mechanism by which the protein contributes to the looping of DNA. Conventional models of the looping...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679585/ https://ncbi.nlm.nih.gov/pubmed/18586040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.088 |
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