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Analysis of the Functional Polymorphism in the Cytochrome P450 CYP2C8 Gene rs11572080 with Regard to Colorectal Cancer Risk

In addition to the known effects on drug metabolism and response, functional polymorphisms of genes coding for xenobiotic-metabolizing enzymes (XME) play a role in cancer. Genes coding for XME act as low-penetrance genes and confer modest but consistent and significant risks for a variety of cancers...

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Detalhes bibliográficos
Main Authors: Ladero, José M., Agúndez, José A. G., Martínez, Carmen, Amo, Gemma, Ayuso, Pedro, García-Martín, Elena
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572883/
https://ncbi.nlm.nih.gov/pubmed/23420707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00278
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