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Polymorphic Cytochrome P450 Enzymes (CYPs) and Their Role in Personalized Therapy
The cytochrome P450 (CYP) enzymes are major players in drug metabolism. More than 2,000 mutations have been described, and certain single nucleotide polymorphisms (SNPs) have been shown to have a large impact on CYP activity. Therefore, CYPs play an important role in inter-individual drug response a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858335/ https://ncbi.nlm.nih.gov/pubmed/24340040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082562 |
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