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Electronic Barcoding of a Viral Gene at the Single-Molecule Level

A new single-molecule approach for rapid and purely electronic discrimination among similar genes is presented. Combining solid-state nanopores and γ-modified synthetic peptide nucleic acid (γPNA) probes, we accurately barcode genes by counting the number of probes attached to each gene, and measuri...

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Detalles Bibliográficos
Main Authors: Singer, Alon, Rapireddy, Srinivas, Ly, Danith H., Meller, Amit
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572535/
https://ncbi.nlm.nih.gov/pubmed/22352964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl300372a
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