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Optical recognition of converted DNA nucleotides for single-molecule DNA sequencing using nanopore arrays

We demonstrate the feasibility of a nanopore based single-molecule DNA sequencing method, which employs multi-color readout. Target DNA is converted according to a binary code, which is recognized by molecular beacons with two types of fluorophores. Solid-state nanopores are then used to sequentiall...

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Bibliografski detalji
Glavni autori: McNally, Ben, Singer, Alon, Yu, Zhiliang, Sun, Yingjie, Weng, Zhiping, Meller, Amit
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883017/
https://ncbi.nlm.nih.gov/pubmed/20459065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl1012147
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