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Optical recognition of converted DNA nucleotides for single-molecule DNA sequencing using nanopore arrays
We demonstrate the feasibility of a nanopore based single-molecule DNA sequencing method, which employs multi-color readout. Target DNA is converted according to a binary code, which is recognized by molecular beacons with two types of fluorophores. Solid-state nanopores are then used to sequentiall...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2883017/ https://ncbi.nlm.nih.gov/pubmed/20459065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl1012147 |
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