Cariprazine, a Dopamine D(3)-Receptor-Preferring Partial Agonist, Blocks Phencyclidine-induced Impairments of Working Memory, Attention Set-Shifting, and Recognition Memory in the Mouse

RATIONALE: A major challenge in the pharmacological treatment of psychotic disorders is the effective management of the associated cognitive dysfunctions. Novel concepts emphasize a potential benefit of partial agonists acting upon dopamine D(2)-like receptors in ameliorating these cognitive deficit...

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Bibliographische Detailangaben
Hauptverfasser: Zimnisky, Ross, Chang, Gloria, Gyertyán, István, Kiss, Béla, Adham, Nika, Schmauss, Claudia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572273/
https://ncbi.nlm.nih.gov/pubmed/23079899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2896-5
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