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Systematic Screens for Proteins That Interact with the Mucolipidosis Type IV Protein TRPML1

Mucolipidosis type IV is a lysosomal storage disorder resulting from mutations in the MCOLN1 gene, which encodes the endosomal/lysosomal Transient Receptor Potential channel protein mucolipin-1/TRPML1. Cells isolated from Mucolipidosis type IV patients and grown in vitro and in in vivo models of thi...

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Autors principals: Spooner, Ellen, McLaughlin, Brooke M., Lepow, Talya, Durns, Tyler A., Randall, Justin, Upchurch, Cameron, Miller, Katherine, Campbell, Erin M., Fares, Hanna
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572064/
https://ncbi.nlm.nih.gov/pubmed/23418601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056780
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