Overexpression of CDCA2 in Human Squamous Cell Carcinoma: Correlation with Prevention of G1 Phase Arrest and Apoptosis

Cell division cycle associated 2 (CDCA2) recruits protein phosphatase 1 to chromatin to antagonize activation of ataxia telangiectasia mutated (ATM)-dependent signal transduction. ATM kinase plays a critical role in the DNA damage response and its phosphorylation cascade to inhibit the p53-MDM2 inte...

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Detalhes bibliográficos
Main Authors: Uchida, Fumihiko, Uzawa, Katsuhiro, Kasamatsu, Atsushi, Takatori, Hiroaki, Sakamoto, Yosuke, Ogawara, Katsunori, Shiiba, Masashi, Bukawa, Hiroki, Tanzawa, Hideki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572040/
https://ncbi.nlm.nih.gov/pubmed/23418564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056381
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