Overexpression of cell cycle regulator CDCA3 promotes oral cancer progression by enhancing cell proliferation with prevention of G1 phase arrest

<p>Abstract</p> <p>Background</p> <p>Cell division cycle associated 3 (CDCA3), part of the Skp1-cullin-F-box (SCF) ubiquitin ligase, refers to a trigger of mitotic entry and mediates destruction of the mitosis inhibitory kinase. Little is known about the relevance of CD...

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Detalhes bibliográficos
Main Authors: Uchida Fumihiko, Uzawa Katsuhiro, Kasamatsu Atsushi, Takatori Hiroaki, Sakamoto Yosuke, Ogawara Katsunori, Shiiba Masashi, Tanzawa Hideki, Bukawa Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2012-07-01
Colecção:BMC Cancer
Assuntos:
Cell division cycle associated 3
Oral squamous cell carcinoma
Proliferation
Cell-cycle arrest
Cyclin-dependent kinase inhibitors
Acesso em linha:http://www.biomedcentral.com/1471-2407/12/321
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