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Structure of a Dengue Virus Envelope Protein Late-Stage Fusion Intermediate

The final stages of dengue virus fusion are thought to occur when the membrane-proximal stem drives the transmembrane anchor of the viral envelope protein (E) toward the fusion loop, buried in the target cell membrane. Crystal structures of E have lacked this essential stem region. We expressed and...

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Detalhes bibliográficos
Main Authors: Klein, Daryl E., Choi, Jason L., Harrison, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571469/
https://ncbi.nlm.nih.gov/pubmed/23236058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02957-12
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