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Integrin and Defensin Modulate the Mechanical Properties of Adenovirus

The propensity for capsid disassembly and uncoating of human adenovirus is modulated by interactions with host cell molecules like integrins and alpha defensins. Here, we use atomic force microscopy (AFM) nanoindentation to elucidate, at the single-particle level, the mechanism by which binding of t...

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Auteurs principaux: Snijder, Joost, Reddy, Vijay S., May, Eric R., Roos, Wouter H., Nemerow, Glen R., Wuite, Gijs J. L.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571403/
https://ncbi.nlm.nih.gov/pubmed/23269786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02516-12
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