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Adenovirus Composition, Proteolysis, and Disassembly Studied by In-depth Qualitative and Quantitative Proteomics

Using high-resolution MS-based proteomics in combination with multiple protease digestion, we profiled, with on average 90% sequence coverage, all 13 viral proteins present in an human adenovirus (HAdV) vector. This in-depth profile provided multiple peptide-based evidence on intrinsic protease acti...

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Detalhes bibliográficos
Main Authors: Benevento, Marco, Di Palma, Serena, Snijder, Joost, Moyer, Crystal L., Reddy, Vijay S., Nemerow, Glen R., Heck, Albert J. R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036278/
https://ncbi.nlm.nih.gov/pubmed/24591515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537498
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