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Cryo-Electron Microscopy Structure of an Adenovirus-Integrin Complex Indicates Conformational Changes in both Penton Base and Integrin

A structure of adenovirus type 12 (HAdV12) complexed with a soluble form of integrin αvβ5 was determined by cryo-electron microscopy (cryoEM) image reconstruction. Subnanometer resolution (8 Å) was achieved for the icosahedral capsid with moderate resolution (27 Å) for integrin density above each pe...

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Main Authors: Lindert, Steffen, Silvestry, Mariena, Mullen, Tina-Marie, Nemerow, Glen R., Stewart, Phoebe L.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology (ASM) 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772687/
https://ncbi.nlm.nih.gov/pubmed/19726496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01214-09
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