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Insight into the Mechanisms of Adenovirus Capsid Disassembly from Studies of Defensin Neutralization

Defensins are effectors of the innate immune response with potent antibacterial activity. Their role in antiviral immunity, particularly for non-enveloped viruses, is poorly understood. We recently found that human alpha-defensins inhibit human adenovirus (HAdV) by preventing virus uncoating and rel...

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Detalhes bibliográficos
Main Authors: Smith, Jason G., Silvestry, Mariena, Lindert, Steffen, Lu, Wuyuan, Nemerow, Glen R., Stewart, Phoebe L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891831/
https://ncbi.nlm.nih.gov/pubmed/20585634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000959
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