Insight into the Mechanisms of Adenovirus Capsid Disassembly from Studies of Defensin Neutralization

Defensins are effectors of the innate immune response with potent antibacterial activity. Their role in antiviral immunity, particularly for non-enveloped viruses, is poorly understood. We recently found that human alpha-defensins inhibit human adenovirus (HAdV) by preventing virus uncoating and rel...

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Autores principales: Smith, Jason G., Silvestry, Mariena, Lindert, Steffen, Lu, Wuyuan, Nemerow, Glen R., Stewart, Phoebe L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891831/
https://ncbi.nlm.nih.gov/pubmed/20585634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000959
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