Early Antigen Presentation of Protective HIV-1 KF11Gag and KK10Gag Epitopes from Incoming Viral Particles Facilitates Rapid Recognition of Infected Cells by Specific CD8(+) T Cells

CD8(+) T cells are major players in antiviral immunity against human immunodeficiency virus type 1 (HIV-1) through recognition of viral epitopes presented on the surface of infected cells. However, the early events involving HIV-1 epitope presentation to CD8(+) T cells remain poorly understood but a...

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Main Authors: Kløverpris, Henrik N., Payne, Rebecca P., Sacha, Jonah B., Rasaiyaah, Jane T., Chen, Fabian, Takiguchi, Masafumi, Yang, Otto O., Towers, Greg J., Goulder, Philip, Prado, Julia G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571362/
https://ncbi.nlm.nih.gov/pubmed/23255798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02131-12
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