Molecular Mechanisms Underlying Oseltamivir Resistance Mediated by an I117V Substitution in the Neuraminidase of Subtype H5N1 Avian Influenza A Viruses

Background. The neuraminidase (NA) inhibitor oseltamivir is widely used to treat patients infected with influenza viruses. An Ile-to-Val change at position 117 in influenza A virus subtype H5N1 NA (NA-I117V) confers a reduction in susceptibility to oseltamivir carboxylate. However, the in vivo relev...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Takano, Ryo, Kiso, Maki, Igarashi, Manabu, Le, Quynh Mai, Sekijima, Masakazu, Ito, Kimihito, Takada, Ayato, Kawaoka, Yoshihiro
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571237/
https://ncbi.nlm.nih.gov/pubmed/23053629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis633
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker