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The Nuclear Magnetic Resonance of CCCC RNA Reveals a Right-Handed Helix, and Revised Parameters for AMBER Force Field Torsions Improve Structural Predictions from Molecular Dynamics

[Image: see text] The sequence dependence of RNA energetics is important for predicting RNA structure. Hairpins with C(n) loops are consistently less stable than hairpins with other loops, which suggests the structure of C(n) regions could be unusual in the “unfolded” state. For example, previous nu...

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Detalhes bibliográficos
Main Authors: Tubbs, Jason D., Condon, David E., Kennedy, Scott D., Hauser, Melanie, Bevilacqua, Philip C., Turner, Douglas H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2013
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571207/
https://ncbi.nlm.nih.gov/pubmed/23286901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3010347
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