Black Raspberry-Derived Anthocyanins Demethylate Tumor Suppressor Genes Through the Inhibition of DNMT1 and DNMT3B in Colon Cancer Cells

We previously reported that oral administration of black raspberry powder decreased promoter methylation of tumor suppressor genes in tumors from patients with colorectal cancer. The anthocyanins (ACs) in black raspberries are responsible, at least in part, for their cancer-inhibitory effects. In th...

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Autors principals: Wang, Li-Shu, Kuo, Chieh-Ti, Cho, Seung-Ju, Seguin, Claire, Siddiqui, Jibran, Stoner, Kristen, Weng, Yu-I, Huang, Tim H.-M., Tichelaar, Jay, Yearsley, Martha, Stoner, Gary D., Huang, Yi-Wen
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570951/
https://ncbi.nlm.nih.gov/pubmed/23368921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635581.2013.741759
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