Two apolipoprotein E mimetic peptides with similar cholesterol reducing properties exhibit differential atheroprotective effects in LDL-R null mice

OBJECTIVE: We investigated two apoE mimetic peptides with similar long-term plasma cholesterol reducing abilities for their effects on atherosclerotic lesions in Western diet-fed female LDL receptor (LDL-R) null mice. METHODS AND RESULTS: Single doses of peptides Ac-hE18A-NH(2) and mR18L were admini...

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Main Authors: Handattu, Shaila P., Nayyar, Gaurav, Garber, David W., Palgunachari, Mayakonda N., Monroe, Candyce E., Keenum, Tamara D., Mishra, Vinod K., Datta, Geeta, Anantharamaiah, G.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570741/
https://ncbi.nlm.nih.gov/pubmed/23159231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2012.10.064
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