Two adjacent domains (141-150 and 151-160) of apoE covalently linked to a class A amphipathic helical peptide exhibit opposite atherogenic effects

OBJECTIVE: We recently described anti-atherogenic properties of the dual domain peptide Ac-hE18A-NH(2) derived by covalently linking the heparin binding domain 141-150 of apoE to 18A, a class A amphipathic helical peptide. In this paper we have compared the properties of Ac-hE18A-NH(2) with the non-...

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Main Authors: Nayyar, Gaurav, Handattu, Shaila P., Monroe, Candyce E., Chaddha, Manjula, Datta, Geeta, Mishra, Vinod K., Keenum, Tamara D., Palgunachari, Mayakonda N., Garber, David W., Anantharamaiah, G.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997865/
https://ncbi.nlm.nih.gov/pubmed/21030022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2010.09.030
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