Oral administration of L-mR18L, a single domain cationic amphipathic helical peptide, inhibits lesion formation in ApoE null mice

We have shown that Ac-hE18A-NH(2), a dual-domain cationic apolipoprotein-mimetic peptide, reduces plasma cholesterol levels in dyslipidemic mice. Two single-domain cationic peptides based on the lytic class L peptide 18L were developed to test the hypothesis that a single-domain cationic amphipathic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Handattu, Shaila P., Datta, Geeta, Epand, Richard M., Epand, Raquel F., Palgunachari, Mayakonda N., Mishra, Vinod K., Monroe, Candyce E., Keenum, Tamara D., Chaddha, Manjula, Anantharamaiah, G. M., Garber, David W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975721/
https://ncbi.nlm.nih.gov/pubmed/20841495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M006916
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