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Bioreducible polymers as a determining factor for polyplex decomplexation rate and transfection

Polyplex formation (complexation) and gene release from the polyplexes (decomplexation) are major events in polymeric gene delivery, however the effect of the decomplexation rate on transfection has been rarely investigated. This study employed mixed polymers of poly(L-lysine) (PLL: MW ~7.4 kDa) and...

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Bibliografische gegevens
Hoofdauteurs: Hwang, Hee Sook, Kang, Han Chang, Bae, You Han
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570707/
https://ncbi.nlm.nih.gov/pubmed/23259985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm301794d
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