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CC12, a P450/Epoxygenase Inhibitor, Acts in the Rat Rostral Ventromedial Medulla to Attenuate Morphine Antinociception
Brain cytochrome P450 epoxygenases were recently shown to play an essential role in mediating the pain-relieving properties of morphine. To identify the CNS sites containing the morphine-relevant P450s, the effects of intracerebral (ic) microinjections of the P450 inhibitor CC12 were determined on m...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570688/ https://ncbi.nlm.nih.gov/pubmed/23298831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.12.030 |
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