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CC12, a P450/Epoxygenase Inhibitor, Acts in the Rat Rostral Ventromedial Medulla to Attenuate Morphine Antinociception

Brain cytochrome P450 epoxygenases were recently shown to play an essential role in mediating the pain-relieving properties of morphine. To identify the CNS sites containing the morphine-relevant P450s, the effects of intracerebral (ic) microinjections of the P450 inhibitor CC12 were determined on m...

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Autors principals: Conroy, Jennie L., Nalwalk, Julia W., Phillips, James G., Hough, Lindsay B.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570688/
https://ncbi.nlm.nih.gov/pubmed/23298831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.12.030
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