Excessive Fibrin Deposition in Nasal Polyps Caused by Fibrinolytic Impairment through Reduction of Tissue Plasminogen Activator Expression

Rationale: Nasal polyps (NPs) are characterized by intense edema or formation of pseudocysts filled with plasma proteins, mainly albumin. However, the mechanisms underlying NP retention of plasma proteins in their submucosa remain unclear. Objectives: We hypothesized that formation of a fibrin mesh...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Takabayashi, Tetsuji, Kato, Atsushi, Peters, Anju T., Hulse, Kathryn E., Suh, Lydia A., Carter, Roderick, Norton, James, Grammer, Leslie C., Cho, Seong H., Tan, Bruce K., Chandra, Rakesh K., Conley, David B., Kern, Robert C., Fujieda, Shigeharu, Schleimer, Robert P.
التنسيق: Artigo
اللغة:Inglês
منشور في: American Thoracic Society 2013
الموضوعات:
Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570641/
https://ncbi.nlm.nih.gov/pubmed/23155140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201207-1292OC
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