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An Experimental Verification of the Predicted Effects of Promoter TATA-Box Polymorphisms Associated with Human Diseases on Interactions between the TATA Boxes and TATA-Binding Protein

Human genome sequencing has resulted in a great body of data, including a stunningly large number of single nucleotide polymorphisms (SNPs) with unknown phenotypic manifestations. Identification and comprehensive analysis of regulatory SNPs in human gene promoters will help quantify the effects of t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Savinkova, Ludmila, Drachkova, Irina, Arshinova, Tatyana, Ponomarenko, Petr, Ponomarenko, Mikhail, Kolchanov, Nikolay
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570547/
https://ncbi.nlm.nih.gov/pubmed/23424617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054626
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