An Experimental Verification of the Predicted Effects of Promoter TATA-Box Polymorphisms Associated with Human Diseases on Interactions between the TATA Boxes and TATA-Binding Protein

Human genome sequencing has resulted in a great body of data, including a stunningly large number of single nucleotide polymorphisms (SNPs) with unknown phenotypic manifestations. Identification and comprehensive analysis of regulatory SNPs in human gene promoters will help quantify the effects of t...

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Detalhes bibliográficos
Main Authors: Savinkova, Ludmila, Drachkova, Irina, Arshinova, Tatyana, Ponomarenko, Petr, Ponomarenko, Mikhail, Kolchanov, Nikolay
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570547/
https://ncbi.nlm.nih.gov/pubmed/23424617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054626
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