The limits of protection by “memory” T cells in Ig(–/–) mice persistently infected with a γ-herpesvirus

Can CD4(+) and CD8(+) “memory” T cells that are generated and maintained in the context of low-level virus persistence protect, in the absence of antibody, against a repeat challenge with the same pathogen? Although immune T cells exert effective, long-term control of a persistent γ-herpesvirus (γHV...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Andreansky, Samita, Liu, Haiyan, Adler, Heiko, Koszinowski, Ulrich H., Efstathiou, Stacey, Doherty, Peter C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2004
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC357044/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14764895/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307320101
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