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PPARγ Activation Attenuates Glycated-Serum Induced Pancreatic Beta-Cell Dysfunction through Enhancing Pdx1 and Mafa Protein Stability

Pancreatic-duodenal homeobox-1 (Pdx1) and v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (Mafa) play important roles in sustaining the pancreatic beta-cell differentiation phenotype. Peroxisome proliferator-activated receptor-γ (PPARγ) is also a regulator of cell differentiation. Our previ...

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Detalhes bibliográficos
Main Authors: Zhu, Yunxia, Ma, Ai, Zhang, Hongxiu, Li, Chaojun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570423/
https://ncbi.nlm.nih.gov/pubmed/23424659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056386
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