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Loss of Function of the Mouse Sharpin Gene Results in Peyer’s Patch Regression
Peyer’s patches (PP) are an important component in the immune response against intestinal pathogens. Two independent, spontaneous mutations in the mouse Sharpin gene (Sharpin(cpdm) and Sharpin(cpdm-Dem)) result in the absence of PP and disrupted splenic white pulp in adult mice, although a full comp...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570409/ https://ncbi.nlm.nih.gov/pubmed/23424624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055224 |
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