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Anti-IL5 decreases the number of eosinophils but not the severity of dermatitis in SHARPIN-deficient mice
Sharpin-deficient (Sharpin(cpdm)) mutant mice develop a chronic eosinophilic dermatitis. To determine the efficacy of eosinophil-depletion in chronic inflammation, Sharpin(cpdm) mice were treated with anti-IL5 antibodies. Mice treated with anti-IL5 had a 90% reduction of circulating eosinophils and...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852468/ https://ncbi.nlm.nih.gov/pubmed/19650867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0625.2009.00944.x |
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