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Inhibition of NFKB signaling retards eosinophilic dermatitis in SHARPIN-deficient mice

The NFKB pathway performs pivotal roles in diverse physiological processes, such as immunity, inflammation, proliferation, and apoptosis. NFKB is kept inactive in the cytoplasm through association with inhibitors (IKB), and translocates to the nucleus to activate its target genes after the IKBs are...

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Autori principali: Liang, Yanhua, Seymour, Rosemarie, Sundberg, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071979/
https://ncbi.nlm.nih.gov/pubmed/20811394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.259
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