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Inhibition of NFKB signaling retards eosinophilic dermatitis in SHARPIN-deficient mice
The NFKB pathway performs pivotal roles in diverse physiological processes, such as immunity, inflammation, proliferation, and apoptosis. NFKB is kept inactive in the cytoplasm through association with inhibitors (IKB), and translocates to the nucleus to activate its target genes after the IKBs are...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071979/ https://ncbi.nlm.nih.gov/pubmed/20811394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.259 |
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