Wiskott-Aldrich syndrome protein–mediated actin dynamics control type-I interferon production in plasmacytoid dendritic cells

Mutations in Wiskott-Aldrich syndrome (WAS) protein (WASp), a regulator of actin dynamics in hematopoietic cells, cause WAS, an X-linked primary immunodeficiency characterized by recurrent infections and a marked predisposition to develop autoimmune disorders. The mechanisms that link actin alterati...

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Main Authors: Prete, Francesca, Catucci, Marco, Labrada, Mayrel, Gobessi, Stefania, Castiello, Maria Carmina, Bonomi, Elisa, Aiuti, Alessandro, Vermi, William, Cancrini, Caterina, Metin, Ayse, Hambleton, Sophie, Bredius, Robbert, Notarangelo, Luigi Daniele, van der Burg, Mirjam, Kalinke, Ulrich, Villa, Anna, Benvenuti, Federica
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570108/
https://ncbi.nlm.nih.gov/pubmed/23337808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20120363
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