HIF-1α downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation

Hypoxia-inducible factor 1 (HIF-1) is a crucial transcription factor for the cellular adaptive response to hypoxia, which contributes to multiple events in cancer biology. MicroRNAs (miRNAs) are involved in almost all cellular activities such as differentiation, proliferation, and apoptosis. In this...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: He, M, Wang, Q-Y, Yin, Q-Q, Tang, J, Lu, Y, Zhou, C-X, Duan, C-W, Hong, D-L, Tanaka, T, Chen, G-Q, Zhao, Q
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569981/
https://ncbi.nlm.nih.gov/pubmed/23059786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.130
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