HIF-1α downregulates miR-17/20a directly targeting p21 and STAT3: a role in myeloid leukemic cell differentiation

Hypoxia-inducible factor 1 (HIF-1) is a crucial transcription factor for the cellular adaptive response to hypoxia, which contributes to multiple events in cancer biology. MicroRNAs (miRNAs) are involved in almost all cellular activities such as differentiation, proliferation, and apoptosis. In this...

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Detalhes bibliográficos
Main Authors: He, M, Wang, Q-Y, Yin, Q-Q, Tang, J, Lu, Y, Zhou, C-X, Duan, C-W, Hong, D-L, Tanaka, T, Chen, G-Q, Zhao, Q
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569981/
https://ncbi.nlm.nih.gov/pubmed/23059786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.130
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