MicroRNAs in the miR-17 and miR-15 families are downregulated in chronic kidney disease with hypertension

BACKGROUND: In older adults (aged 70–74 years), African-Americans have 4-fold higher risk of developing hypertension-attributed end-stage renal disease (ESRD) than European-Americans. A hypothesized mechanism linking hypertension and progressive chronic kidney disease (CKD) is the innate immune resp...

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Veröffentlicht in:PLoS One
Hauptverfasser: Nandakumar, Priyanka, Tin, Adrienne, Grove, Megan L., Ma, Jianzhong, Boerwinkle, Eric, Coresh, Josef, Chakravarti, Aravinda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542606/
https://ncbi.nlm.nih.gov/pubmed/28771472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176734
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